Spectral Imaging with Multi-Element Analysis
Supervisor: Dr. Ted McGowan and Dr. Leo Creedon
Funding Body: ITSligo Presidents Bursary
The main objective of the project is to develop multi-element/multi/component analytical techniques for monitoring changes and generating information on both human and animal bone. The dietary regime and health of animals will be monitored through changes in their bone components and structure. Methodology for a range of modern analytical techniques (e.g. x-ray fluorescence (XRF), atomic absorption spectrometry (AAS), inductively coupled plasma-atomic emission spectrometry (ICP-AES) and Fourier transform Infrared spectroscopy (FTIR)) will be developed and validated using bovine bone samples. Chemometric techniques will be applied to the multi-element data in order to identify related components for monitoring changes within bone. The research will be applied to monitor changes in bone resulting from animal health status, diet and medical treatments. The research has the potential to be extended to the study of human bone and to provide techniques essential to the development of new pharmaceuticals and medical devices.